Biotin (vitamin B7) is one of the most marketed supplements for hair, skin, and nail health — and one of the most frequently misunderstood. For people with adequate biotin levels, supplementation produces little visible effect. For people who are deficient — which is more common on restricted diets, after periods of rapid weight loss, or on GLP-1 medication — biotin supplementation can meaningfully support the structural proteins that keep hair, skin, and nails healthy. Lily & Loaf Biotin Plus provides 5,000 mcg per serving — a high-dose formula specifically targeted at people whose nutritional needs have changed.

What does biotin actually do?
Biotin is a water-soluble B vitamin that acts as a cofactor for several carboxylase enzymes involved in:
- Fatty acid synthesis (relevant to skin moisture and barrier function)
- Amino acid metabolism (relevant to hair protein production)
- Gluconeogenesis (relevant to blood sugar regulation)
- The production of keratin — the structural protein in hair, skin, and nails
Does biotin actually help hair loss?
The evidence for biotin and hair loss is more nuanced than supplement marketing suggests:
- For people with biotin deficiency: strong evidence — hair loss and brittle nails are classic signs of deficiency, and correcting it resolves these symptoms
- For people without deficiency: limited evidence for additional benefit beyond normal levels
- For GLP-1-related hair loss (telogen effluvium): biotin addresses one of the nutritional deficiencies that can worsen or prolong telogen effluvium — reduced protein and micronutrient intake. It is a supporting intervention, not a cure
The implication: if you are losing hair on Mounjaro and your diet has been reduced significantly, biotin supplementation is a reasonable protective measure. If your hair loss predates dietary restriction and you eat a complete diet, additional biotin is less likely to produce visible change.
Who is Biotin Plus for?
- People experiencing hair thinning or breakage during weight loss or GLP-1 treatment
- People on calorie-restricted diets where food variety is reduced
- People with brittle nails that break or peel easily
- Vegans and vegetarians (biotin from food is concentrated in egg yolks — limited in plant-heavy diets)
- Pregnant or breastfeeding women (biotin requirements increase — always check with GP)
Biotin Plus vs alternatives
| Product | Biotin dose | Additional nutrients | Vegan | Price/month |
|---|---|---|---|---|
| Lily & Loaf Biotin Plus | 5,000 mcg | Check label for additional B vitamins | ✅ Yes | ~£15–20 |
| Nature’s Bounty Biotin 10,000 mcg | 10,000 mcg | None | ❌ Gelatin capsule | ~£12 |
| Solgar Biotin 1000 mcg | 1,000 mcg | None | ✅ | ~£10 |
| Holland & Barrett Biotin | 1,000–5,000 mcg | None | Check label | ~£8 |
At 5,000 mcg, Lily & Loaf Biotin Plus sits at the standard clinical supplementation dose for hair and skin support. Nature’s Bounty offers a higher dose (10,000 mcg) at a lower price — but the capsule is gelatin-based (not vegan). For people who are already taking Daily Fuel (which contains biotin as part of its 15-mineral formula), check for overlap before adding Biotin Plus separately.
Lily & Loaf — Recommended Pick
Biotin Plus
✅ 90-day money-back guarantee | ✅ Free UK delivery over £40 | ✅ UK-based brand
5,000 mcg biotin · Vegan · Gluten-free · Hair, skin and nails
Frequently Asked Questions
Does biotin actually work for hair loss?
For people with biotin deficiency (more common on restricted diets), correcting deficiency visibly improves hair quality and reduces shedding. For people with adequate biotin levels, high-dose supplementation has limited evidence. On GLP-1 medication where food intake is reduced, biotin is a reasonable supportive supplement.
Can I take Biotin Plus alongside Daily Fuel?
Check for overlap — Daily Fuel contains biotin as part of its vitamin complex. You may already be getting a meaningful biotin dose from your protein shake. Adding Biotin Plus separately would increase your total daily biotin significantly — not harmful (biotin is water-soluble and excess is excreted) but potentially unnecessary.
Does high-dose biotin interfere with lab tests?
Yes — this is important. High-dose biotin supplementation can interfere with certain thyroid function tests and troponin assays (heart enzyme tests), producing false results. If you are having blood tests, stop biotin supplementation for at least 48 hours beforehand and tell your GP.
How long before biotin improves hair quality?
Hair grows approximately 1–1.5cm per month. Improvements in new hair growth are typically noticed at 3–4 months of consistent use. Reduced shedding may be noticed earlier if deficiency is the cause.
Is Biotin Plus suitable for vegans?
Yes — Lily & Loaf Biotin Plus is listed as vegan and gluten-free. Many budget biotin supplements use gelatin capsules — check labels when comparing.
Related: Hair Loss on Mounjaro UK | Lily & Loaf Collagen Plus Review
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